General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ Tango™ HRH3-bla U2OS DA Assay Kit
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ AGTRL1-bla U2OS Cells
The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ LanthaScreen™ ERK2 A375 Cell Line
The Map Kinase (MapK) signal transduction cascade is activated by growth factors such as EGF, PDGF, and HGF.
Thermo Scientific™ CellSensor™ ISRE-bla HEK293T Cell Line
The CellSensor™ ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.
Thermo Scientific™ CellSensor™ ISRE-bla RA-1 Cell Line
The CellSensor™ ISRE-bla RA-1 Cell Line contains the beta-lactamase (bla) gene under the control of the interferon-stimulated response element (ISRE).
Thermo Scientific™ Tango™ GPR39-bla U2OS Cells
Tango™ GPR39-bla U2OS cells contain the orphan human G-protein Coupled Receptor 39 (GPR39) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ Gα15-NFAT CHO-K1 DA Assay Kit
The GeneBLAzer™ Gα15-NFAT CHO-K1 DA (Division Arrested) cell line contains the promiscuous G protein, Gα15, stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ GR DA Assay Kit
GeneBLAzer™GR DA (Division Arrested) cells and GR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Gluocorticoid receptor (GR) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ GeneBLAzer™ NTSR1 CHO-K1 DA Assay Kit
The GeneBLAzer™ NTSR1 CHO-K1 DA cells contain the human Neurotensin Receptor 1 (NTSR1) stably integrated into the GeneBLAzer™ Gqo5-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ HTR2A-bla U2OS Cells
The Tango™ HTR2A-bla U2OS cells contain the human Serotonin Type 2A receptor (HTR2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ ADRA2A-bla U2OS DA Assay Kit
The Tango™ ADRA2A-bla U2OS cells contain the human Adrenergic, Alpha-2A-, Receptor (ADRA2A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 Cells
GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.