Test
Inhibits NF-κB activation
CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).
Used as cell-permeable, irreversible inhibitor of caspase activity. R&D Systems Pan Caspase Inhibitor Z-VAD-FMK binds to the active site of activated proteases irreversibly and inhibits apoptosis.
MEK inhibitor
Potent and selective Lck and Src inhibitor; also inhibits SIK
Potent and selective K2P3.1 (TASK-1) channel blocker
Highly selective and potent non-peptide NPY Y5 receptor antagonist
Potent VEGFR inhibitor; also inhibits other RTKs
S1P2 receptor antagonist
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
Glucokinase activator
Highly potent and selective JNK3 inhibitor
Selective inhibitor of Rac1-GEF interaction; antioncogenic
Red-fluorescent DNA stain; membrane impermeant to live cells. Pi staining differentiates live and dead cells