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Tocris™ 1A-116

Rac1 inhibitor; blocks Rac1-P-Rex1 interaction

Brand: Tocris™ 6701/10

1598.02 DKK valid until 2024-12-16
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Product Code. 18054522

1975.00 DKK / 10mg

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Description

1A-116 is a Rac1 inhibitor. Reduces intracellular Rac1-GTP levels and blocks Rac1-P-Rex1 interaction in vitro. Exhibits no effect on GTPase activity of closely related Cdc42. Displays antiproliferative, anti-invasive and pro-apoptotic activity in several cancer cell lines. Exhibits antimetastatic activity in vivo. Also restores antiproliferative effects of Tamoxifen (Cat. No. 6342) in resistant breast cancer cell.

Specifications

Chemical Name or Material	N-(3,5-Dimethylphenyl)-N-[2-(trifluoromethyl)phenyl]guanidine
Quantity	10 mg
Formula Weight	307.31
Purity	98%

CAS	1430208-73-3
Molecular Formula	C₁₆H₁₆F₃N₃
Product Type	Inhibitor

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