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3-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals

Product Code. 11349479
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Quantity:
5 g
25 g
100 g
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3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.

Solubility
Soluble in acetone and methanol.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 621-59-0
Molecular Formula C8H8O3
Molecular Weight (g/mol) 152.149
MDL Number MFCD00003369
InChI Key JVTZFYYHCGSXJV-UHFFFAOYSA-N
Synonym isovanillin, isovanilline, 3-hydroxy-p-anisaldehyde, 5-formylguaiacol, benzaldehyde, 3-hydroxy-4-methoxy, iso-vanillin, 3-hydroxyanisaldehyde, isovanilin, isovanicaline, 3-hydroxy-4-methoxy-benzaldehyde
PubChem CID 12127
IUPAC Name 3-hydroxy-4-methoxybenzaldehyde
SMILES COC1=C(C=C(C=C1)C=O)O

Specifications

Melting Point 112°C to 116°C
Density 1.2
Boiling Point 179°C (15 mmHg)
Flash Point >110°C (230°F)
Quantity 5 g
Beilstein 1073021
Sensitivity Air and light sensitive
Solubility Information Soluble in acetone and methanol.
Formula Weight 152.15
Percent Purity 98%
Chemical Name or Material 3-Hydroxy-4-methoxybenzaldehyde
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RUO – Research Use Only

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