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  8. 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%, Thermo Scientific Chemicals

5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside, 98%, Thermo Scientific Chemicals

Product Code. 15450387
50 mg
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Quantity:
50 mg
200 mg
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This item is not returnable. View return policy

Description

Activator of AMP-activated protein kinase (AMPK)

5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes.

Solubility
Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at less than 1mg/ml

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 2627-69-2
Molecular Formula C9H14N4O5
Molecular Weight (g/mol) 258.23
MDL Number MFCD00869751
InChI Key RTRQQBHATOEIAF-UUOKFMHZSA-N
Synonym acadesine, aica-riboside, aicar, arasine, aica riboside, aic-riboside, acadesina, acadesinum, 5-amino-1-beta-d-ribofuranosyl-1h-imidazole-4-carboxamide, protara
PubChem CID 17513
ChEBI CHEBI:28498
IUPAC Name 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
SMILES NC(=O)C1=C(N)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Specifications

Melting Point 214°C to 215°C
Color Brown
Quantity 50 mg
Merck Index 14,16
Solubility Information Soluble in DMSO at 2mg/ml; Soluble in water or ethanol at less than 1mg/ml
Formula Weight 258.23
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside

Safety and Handling

compliance-icons
Product Identifier
  • 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
 Supplemental information
  • MIXTURE LIST-Contains : 5-amino-1-.beta.-D-ribofuranosyl-1H-Imidazole-4-carboxamide
SDS

RUO – Research Use Only

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