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Acifran, Tocris Bioscience™

Product Code. 30001452
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors

Hypolipidemic agent. Exhibits higher potency than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC50 values are 1.3 and 4.2 μM respectively). Reduces serum triglycerides and circulating LDL-cholesterol in vivo, without affecting liver weight or liver enzymes.

Chemical Identifiers

CAS 72420-38-3
Molecular Formula C12H10O4
Molecular Weight (g/mol) 218.208
InChI Key DFDGRKNOFOJBAJ-UHFFFAOYSA-N
Synonym acifran, reductol, acifran usan:inn, acifranum inn-latin, unii-fp3llw01bl, unii-61iz92gn57, fp3llw01bl, 2-furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid, +--4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furoic acid
PubChem CID 51576
IUPAC Name 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
SMILES CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2

Specifications

Quantity 10 mg
Formula Weight 218.21
Percent Purity >99%
Chemical Name or Material Acifran
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