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Tocris Bioscience™ (±)-AMG 487 Product Code.: 30001657
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Tocris Bioscience™ (±)-AMG 487
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Product Code. 30001657
10 mg, 10mg
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 30001657

Brand: Tocris Bioscience™ 4487/10

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This item is not returnable. View return policy

Description

CXCR3 antagonist; inhibits cell migration and metastasis

(±)-AMG 487 is an antagonist of CXCR3; inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3 (IC50 values are 8.0 and 8.2 nM respectively). Inhibits CXCR3-mediated cell migration by the chemokines IP-10, ITAC and MiG in vitro (IC50 values are 8, 15 and 36 nM respectively). Also shown to inhibit lung metastasis in a mouse model of metastatic breast cancer.

This product is racemic.

Greener Choice Claims
  • Environmental benefits include:
    • Ozone-Safe or Safe for the Ozone Layer
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 947536-03-0
Molecular Formula C32H28F3N5O4
Molecular Weight (g/mol) 603.602

Specifications

Quantity 10 mg
Formula Weight 603.59
Purity >98%
Chemical Name or Material (±)-AMG 487
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