Invitrogen™ Coronin 1A Polyclonal Antibody

Description

PA1-10022 was made against the C-terminal peptide of human coronin 1a chemically coupled to keyhole limpet hemocyanin carrier protein. PA1-10022 is also known to work on many mammalian species both on western blots and on cells grown in tissue culture.

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.