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Description
ARL 67156 trisodium salt is a selective NTPDase inhibitor (pIC50 = 4.62 and 5.1 in human blood and rat vas deferens respectively). ARL 67156 prevents vascular calcification and extends longevity in Hutchinson-Gilford progeria syndrome mice. ARL 67156 increases neurogenic contract response to nerve stimulation. ARL 67156 enhances parasympathetic neurotransmission in guinea-pig urinary bladder.

Specifications
Specifications
CAS | 1021868-83-6 |
Molecular Formula | C15H24Br2N5Na3O12P3 |
Quantity | 10 mg |
Synonym | arl 67156 trisodium salt |
InChI Key | BBYLOOHIKBMBIW-TZRPAKANSA-N |
SMILES | CCN(CC)C1=NC=NC2=C1N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Br)Br)O)O)O.[Na].[Na].[Na] |
IUPAC Name | [dibromo-[[[(2R,3S,4R,5R)-5-[6-(diethylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid;sodium |
Molecular Weight (g/mol) | 788.079 |
PubChem CID | 131843136 |
Formula Weight | 785.06 |
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ARL 67156 trisodium salt, Tocris Bioscience™ >
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