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ARL 67156 trisodium salt, Tocris Bioscience™

Product Code. 30001225
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Quantity:
10 mg
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This item is not returnable. View return policy

Description

NTPDase inhibitor

ARL 67156 trisodium salt is a selective NTPDase inhibitor (pIC50 = 4.62 and 5.1 in human blood and rat vas deferens respectively). ARL 67156 prevents vascular calcification and extends longevity in Hutchinson-Gilford progeria syndrome mice. ARL 67156 increases neurogenic contract response to nerve stimulation. ARL 67156 enhances parasympathetic neurotransmission in guinea-pig urinary bladder.

Specifications

CAS 1021868-83-6
Molecular Formula C15H24Br2N5Na3O12P3
Quantity 10 mg
Synonym arl 67156 trisodium salt
InChI Key BBYLOOHIKBMBIW-TZRPAKANSA-N
SMILES CCN(CC)C1=NC=NC2=C1N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Br)Br)O)O)O.[Na].[Na].[Na]
IUPAC Name [dibromo-[[[(2R,3S,4R,5R)-5-[6-(diethylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid;sodium
Molecular Weight (g/mol) 788.079
PubChem CID 131843136
Formula Weight 785.06
Percent Purity >98%
Chemical Name or Material ARL 67156 trisodium salt
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