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Tocris Bioscience™ Asenapine maleate
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
Brand: Tocris Bioscience™ 3737/50
4225.38 DKK valid until 2024-12-16
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Description
Asenapine maleate is a novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8.21 for 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT6, 5-HT7, D1, D2L, D2S, D3, D4, α1A, α2A, α2B, α2C, H1 and H2 receptors respectively). Displays no appreciable affinity for muscarinic receptors. Exhibits potent activity in animal models predictive of antipsychotic efficacy.Specifications
| >98% | |
| Asenapine maleate | |
| Asenapine maleate |
| 50 mg | |
| 401.84 |
For Research Use Only