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Tocris Bioscience™ BAY 1797

Selective P2X4 antagonist

1465.00 DKK - 5855.00 DKK

Specifications

Chemical Name or Material N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide
CAS 2055602-83-8
Target P2X4
Molecular Formula C20H17ClN2O4S
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18729266
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Tocris Bioscience™
7573/10
10 mg
1465.00 DKK
10mg
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18788806
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Tocris Bioscience™
7573/50
50 mg
5855.00 DKK
50mg
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Description

Description

BAY 1797 is a selective purinergic P2X4 receptor antagonist (IC50 values are 108, 112 and 233 nM for the human, mouse and rat P2X4, respectively). It is selective for P2X4 over P2X3, P2X7, and P2X1 receptors (IC50 values are 8.3, 10.6 and >50 μM, respectively, for the human receptors). BAY 1797 dose-dependently reduces prostaglandin E2 levels and exhibits anti-inflammatory and analgesic effects in an in vivo model of inflammatory pain. Orally active.
Specifications

Specifications

N-[3-(Aminosulfonyl)-4-(3-chlorophenoxy)phenyl]benzeneacetamide
2055602-83-8
P2X4
C20H17ClN2O4S
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Safety and Handling

Safety and Handling

Recommended Storage : Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

SDS
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Documents

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