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Carbamazepine, Tocris Bioscience™

Product Code. 18772704
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Quantity:
50 mg
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This item is not returnable. View return policy

Description

Inhibitor of neuronal voltage-gated Na+ channels; anticonvulsant

Inhibitor of neuronal voltage-gated Na+ channels. Exhibits anticonvulsant activity. Potentiates GABA-induced Cl- currents in HEK 293 cells expressing the GABAA receptor α1β2γ2 subtype combination. Can induce autophagy by inhibiting inositol synthesis. Also delays disease onset and prolongs survival in a mouse amyotrophic lateral sclerosis (ALS) model, as well as reducing motor neuron loss and altered muscle morphology.

Specifications

CAS 298-46-4
Molecular Formula C15H12N2O
MDL Number MFCD00005073
Quantity 50 mg
Synonym carbamazepine, tegretol, 5h-dibenzo b,f azepine-5-carboxamide, carbamazepen, carbazepine, finlepsin, carbamezepine, equetro, tegretal, biston
InChI Key FFGPTBGBLSHEPO-UHFFFAOYSA-N
SMILES NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
IUPAC Name 2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,9,11,13-heptaene-2-carboxamide
Molecular Weight (g/mol) 236.27
PubChem CID 2554
ChEBI CHEBI:3387
Formula Weight 236.27
Percent Purity >99%
Chemical Name or Material Carbamazepine
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