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  8. CI 976, Tocris Bioscience™

CI 976, Tocris Bioscience™

Product Code. 18095882
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Quantity:
10 mg
50 mg
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Description

Selective ACAT inhibitor

Selective acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibitor (IC50 = 0.073 μM). Lowers non-high density lipoprotein (HDL)-cholesterol and increases HDL-cholesterol concentrations in rats with pre-established dyslipidemia. Orally active. Also inhibits Golgi-associated LPL acyltransferase (LPAT) activity (IC50 = 15 μM).

Chemical Identifiers

CAS 114289-47-3
Molecular Formula C23H39NO4
Molecular Weight (g/mol) 393.568
InChI Key WAFNZAURAWBNDZ-UHFFFAOYSA-N
Synonym 2,2-dimethyl-n-2,4,6-trimethoxyphenyl dodecanamide, chembl22373, unii-8653iq20ea, dodecanamide,2,2-dimethyl-n-2,4,6-trimethoxyphenyl, dodecanamide, 2,2-dimethyl-n-2,4,6-trimethoxyphenyl, 2,2-dimethyl-dodecanoic acid 2,4,6-trimethoxy-phenyl-amide, acmc-1cuxf, d0d1xg, ci hplc , solid
PubChem CID 122327
IUPAC Name 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
SMILES CCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC

Specifications

Quantity 10 mg
Formula Weight 393.57
Percent Purity >98%
Chemical Name or Material CI 976
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