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Molecular Probes™ Click-IT™ Succinimidyl Ester DIBO Alkyne, for copper free click chemistry
Click-IT™ Succinimidyl Ester DIBO Alkyne, for copper free click chemistry
Brand: Molecular Probes™ C10414
This item is not returnable.
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Description
Conjugates prepared with the amine-reactive alkyne, succinimidyl ester can be detected with an azide-containing molecule in a Copper Free click chemistry reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur, and with the elimination of copper, no detectable damage to cells or proteins. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.
Specifications
Click-IT™ Succinimidyl Ester DIBO Alkyne, 1mg, Off White, Solid, 488.54 Molecular Weight, C28H28N2O6 Molecular Formula, Soluble in DMSO (Dimethylsulfoxide), Used for Labeling Chemistry Applications | |
Labeling chemistry | |
Click-IT™ Succinimidyl Ester DIBO Alkyne | |
≤-20°C | |
Off-White |
Solid | |
1 mg | |
488.54kDa | |
Unconjugated |
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Product Title
Molecular Probes™ Click-IT™ Succinimidyl Ester DIBO Alkyne, for copper free click chemistry > 1mg
For Research Use Only. Not for use in diagnostic procedures.
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