Learn More
Tocris Bioscience™ DL-AP5 Sodium salt
Potent and selective NMDA antagonist; sodium salt of DL-AP5
Brand: Tocris Bioscience™ 3693/50
Description
DL-AP5 Sodium salt is the sodium salt of DL-AP5 (Cat. No. 0105) and a racemic mixture of the D- and L-isomers of AP5, a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity. D-AP5 (Cat. No. 0106) is the more active isomer and displays approximately 52-fold higher potency than the L-isomer, L-AP5 (Cat. No. 0107). In vitro D-AP5 reduces NMDA-induced depolarization of cortical neurons, with no effect on the response to L-Quisqualic acid (Cat. No. 0188) or Kainic acid (Cat. No. 0222). Following spinal injection of D-AP5, NMDA-response is rapidly reduced, with no effect seen on spontaneously active neurons.DL mixture, D-isomer and L-isomer also available.

Specifications
>98% | |
DL-AP5 Sodium salt | |
DL-AP5 Sodium salt |
50 mg | |
219.11 |
Product Suggestions
Customers who viewed this item also viewed
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
For Research Use Only