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G418 disulfate, Cell Culture Reagent, Thermo Scientific Chemicals Product Code.: 15444999
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G418 disulfate, Cell Culture Reagent, Thermo Scientific Chemicals

Artikelnummer. 15444999
5 g
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Quantity:
5 g
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Product Code. 15444999

Brand: Thermo Scientific Alfa Aesar J62671.06

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Beschreibung

G418 sulfate, geneticin, CAS # 108321-42-2, is an antibiotic closely related to Gentamicin B, the common aminoglycoside antibiotic.

G418 disulfate is an aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths. It prevents protein synthesis by blocking the elongation step in prokaryotic and eukaryotic ribosomes. It is used as a selection agent for G418 resistant bacteria or fungi after transformation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• G418 sulfate (geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea
• G418 is a bacteriostatic that prevents polypeptide formation by inhibiting the elongation step of polypeptide synthesis
Applications
• G418 sulfate can be used for selection of genetically engineered cells in both eukaryotes and prokaryotes
• Laboratory grade for applications such as biochemistry

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 108321-42-2
Molecular Formula C20H44N4O18S2
Molecular Weight (g/mol) 692.70
MDL Number MFCD00058314
InChI Key UHEPSJJJMTWUCP-KETIWVBHNA-N
Synonym Geneticin disulfate
PubChem CID 134129582
SMILES OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O

Spezifikation

Type G418 Disulfate
Physical Form Powder
Color White
Quantity 5 g
Solubility Information Soluble in water.
IUPAC Name (2R,3R,4R,5R)-2-[(1S,2R,3R,4S,6R)-4,6-diamino-3-[(2S,3S,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
Formula Weight 692.71
Grade Cell Culture
Chemical Name or Material G418 disulfate

Produktvorschläge

Certificates

Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberR02L020 Certificate TypeCertificate of Analysis Date17/05/2025 Catalog NumberJ62671.03,J62671.14,J62671.06
Lot NumberP13L006 Certificate TypeCertificate of Analysis Date17/03/2025 Catalog NumberJ62671.14,J62671.03,J62671.06
Lot NumberX14K025 Certificate TypeCertificate of Analysis Date05/11/2024 Catalog NumberJ62671.03,J62671.14,J62671.06
Lot NumberU06K034 Certificate TypeCertificate of Analysis Date19/08/2024 Catalog NumberJ62671.03,J62671.14,J62671.06
Lot NumberR09K015 Certificate TypeCertificate of Analysis Date23/05/2024 Catalog NumberJ62671.03,J62671.14,J62671.06

Sicherheit und Handhabung

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Produktidentifikator
  • G418 disulfate, Cell Culture Reagent
 Signalwort
  • Danger
 Gefahrenkategorie
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Gefahrenhinweis
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
 Sicherheitshinweis
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
 Ergänzende Informationen
  • MIXTURE LIST-Contains : G418 disulfate
Sicherheitsdatenblatt (SDS)

RUO – Research Use Only

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