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Tocris Bioscience™ Geldanamycin

Selective Hsp90 inhibitor

Brand: Tocris Bioscience™ 1368/1

Product Code. 18065182

3205.00 DKK / 1mg

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Description

Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.

Specifications

Quantity	1 mg
Assay	>98%
Molecular Formula	C₂₉H₄₀N₂O₉
Solubility	Soluble to 10 mM in DMSO

Content And Storage	Desiccate at -20°C
CAS	30562-34-6
Formula Weight	560.64g/mol

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Tocris Bioscience™ Geldanamycin

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