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Thermo Scientific™ GeneBLAzer™ VPAC1-CRE-bla CHO-K1 Cells
GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells contain the human Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 1 (VPAC1) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Brand: Thermo Scientific™ K1705
This item is not returnable.
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Description
CellSensor™ CRE-bla CHO-K1 cells (Cat. no. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of VIP. In addition, GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
VPAC1 has been implicated in a wide range of disorders, including Parkinson's disease, septic shock, rheumatoid arthritis, multiple sclerosis, Crohn's disease, and autoimmune diabetes. VPAC1-mediated signaling has also been shown to play a role in HIV infection.
Specifications
| NM_004624 | |
| Dividing Cells | |
| Fluorescence | |
| VPAC1 | |
| GeneBLAzer™ | |
| BLA (Beta-Lactamase) | |
| CHO-K1 | |
| GPCR |
| Cell-based beta lactamase reporter gene | |
| Contents: K1705 GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells (LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells • GeneBLAzer™ VPAC1-CRE-bla CHO-K1 Assay Protocol • Certificate of Analysis Storage: The GeneBLAzer™ VPAC1-CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
| FRET | |
| Single Cell Clone Origin | |
| 2 x 106 Cells | |
| VPAC1 | |
| GeneBLAzer™ |
For Research Use Only. Not for use in diagnostic procedures.