missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. 18094722

Tocris Bioscience™ Go 6976

Artikelnummer. 18094722
500 μg
Klik for at se tilgængelige muligheder
Mængde:
500 μg
Denne vare kan ikke returneres. Se returpolicy
Denne vare kan ikke returneres. Se returpolicy

Description

Potent protein kinase C inhibitor; selective for α and β isozymes

Go 6976 is a potent protein kinase C (PKC) inhibitor (IC50 = 7.9 nM). Discriminates between Ca2+-dependent and -independent isoforms of PKC in vitro; selectively inhibits PKCα and PKCβ1 (IC50 values are 2.3 and 6.2 nM respectively). Does not inhibit the activity of PKCδ, -ε, or -ζ (IC50 > 3μM). Also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC50 values are 5, 30, 130 and 370 nM respectively), PKCμ (PKD1) and the mitotic spindle checkpoint.
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile
CAS 136194-77-9
Mængde 500 μg
Mål Protein Kinase C Inhibitors
Molekylær formel C24H18N4O
Renhed 95%
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Tocris Bioscience™ Go 6976 >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.