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  7. GR 113808, Tocris Bioscience™

GR 113808, Tocris Bioscience™

Product Code. 30001234
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective 5-HT4 antagonist

Potent, selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, and Kd = 0.15 nM for binding to cloned human 5-HT4 receptors). Displays > 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors.

Chemical Identifiers

CAS 144625-51-4
Molecular Formula C19H27N3O4S
Molecular Weight (g/mol) 393.50
MDL Number MFCD00912901
InChI Key MOZPSIXKYJUTKI-UHFFFAOYSA-N
Synonym unii-zt350oyt3i, zt350oyt3i, 1-2-methylsulfonylamino ethyl-4-piperidinyl methyl 1-methyl-1h-indole-3-carboxylate, 1h-indole-3-carboxylic acid, 1-methyl-, 1-2-methylsulfonyl amino ethyl-4-piperidinyl methyl ester, 1-2-methylsulfonyl amino ethyl piperidin-4-yl methyl 1-methyl-1h-indole-3-carboxylate, 1-2-methanesulfonamidoethyl piperidin-4-yl methyl 1-methylindole-3-carboxylate, 1-2-methylsulfonyl-amino ethyl-4-piperidinyl methyl 1-methyl-1h-indole-3-carboxylate, 1-methyl-1h-indole-3-carboxylic acid, 1-2-methylsulfonyl amino ethyl-4-piperidinyl methyl ester, tocris-1322, lopac-g-5918
PubChem CID 119376
ChEBI CHEBI:73380
IUPAC Name [1-(2-methanesulfonamidoethyl)piperidin-4-yl]methyl 1-methyl-1H-indole-3-carboxylate
SMILES CN1C=C(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)C2=CC=CC=C12

Specifications

Quantity 10 mg
Formula Weight 393.5
Percent Purity >98%
Chemical Name or Material GR 113808
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