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Gibco™ Human GASP-1 Recombinant Protein, PeproTech®
Recombinant Protein
Brand: Gibco™ 120-41-100UG
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Description
Recombinant Human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions. The calculated molecular weight of Recombinant Human GASP-1 is 59.9 kDa. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain.
Specifications
| Q8TEU8 | |
| protein with no preservative | |
| 59.9 kDa | |
| 100 μg | |
| RUO | |
| 2610304F08Rik; AY100450; Gasp1; GASP-1; Growth and differentiation factor-associated serum protein 1; hGASP-1; mGASP-1; multivalent protease inhibitor protein; RGD1305361; UNQ9235/PRO31996; WAP four-disulfide core domain 20 B; WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein; WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; WAP, FS, Ig, two KU and NTR module related protein; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WFDC20B; WFIKKN2; WFIKKN-related protein; WFIKKNRP | |
| WFIKKN2 | |
| Unconjugated | |
| LPPIRYSHAG ICPNDMNPNL WVDAQSTCRR ECETDQECET YEKCCPNVCG TKSCVAARYM DVKGKKGPVG MPKEATCDHF MCLQQGSECD IWDGQPVCKC KDRCEKEPSF TCASDGLTYY NRCYMDAEAC SKGITLAVVT CRYHFTWPNT SPPPPETTMH PTTASPETPE LDMAAPALLN NPVHQSVTMG ETVSFLCDVV GRPRPEITWE KQLEDRENVV MRPNHVRGNV VVTNIAQLVI YNAQLQDAGI YTCTARNVAG VLRADFPLSV VRGHQAAATS ESSPNGTAFP AAECLKPPDS EDCGEEQTRW HFDAQANNCL TFTFGHCHRN LNHFETYEAC MLACMSGPLA ACSLPALQGP CKAYAPRWAY NSQTGQCQSF VYGGCEGNGN NFESREACEE SCPFPRGNQR CRACKPRQKL VTSFCRSDFV ILGRVSELTE EPDSGRALVT VDEVLKDEKM GLKFLGQEPL EVTLLHVDWA CPCPNVTVSE MPLIIMGEVD GGMAMLRPDS FVGASSARRV RKLREVMHKK TCDVLKEFLG LH | |
| CHO cells | |
| ≥ 95% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 124857 | |
| Human GASP-1 | |
| CHO cells | |
| <1 EU/ μg | |
| GASP1 | |
| Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 ug/ml in the presence of 5 ng/ml of human Myostatin (GDF-8). | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Product Title
Gibco™ Human GASP-1 Recombinant Protein, PeproTech® > 100 μg; Unlabeled
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