Invitrogen™ Human ITIH1 Synthetic Peptide

Description

ITI-HC1 Synthetic Peptide, PEP-301, from Invitrogen™.

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]). This peptide corresponds to amino acids Q(383) VQESLPELSN (393) of human ITI-HC1 and can be used as a blocking peptide with polyclonal antibody PA1-1755.