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Invitrogen™ Human NXT1 (aa 53-76) Control Fragment Recombinant Protein Product Code.: 30197691

Invitrogen™ Human NXT1 (aa 53-76) Control Fragment Recombinant Protein

Product Code. 30197691
100 μL, 100µL
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Quantity:
100 μL
Unit Size:
100µL
This item is not returnable. View return policy

Product Code. 30197691

Brand: Invitrogen™ RP106147

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65471 (PA5-65471. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9UKK6
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 29107
Name Human NXT1 (aa 53-76) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1110001N02Rik; MTR2; NTF2-like export factor 1; NTF2-related export protein 1; NT x 2-like export factor1; nuclear transport factor 2 like export factor 1; nuclear transport factor 2-like export factor 1; NUTF-like export factor 1; NXT1; P15; Protein p15
Common Name NXT1
Gene Symbol NXT1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SGQESLSEFFEMLPSSEFQISVVD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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