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Gibco™ Human R-Spondin-3 Recombinant Protein, PeproTech® Product Code.: 17831373
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Gibco™ Human R-Spondin-3 Recombinant Protein, PeproTech®

Product Code. 17831373
20 μg, 20µg
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Quantity:
1 mg
100 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
1mg
20µg
250µg
500µg
5µg
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Product Code. 17831373

Brand: Gibco™ 1204420UG

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This item is not returnable. View return policy

Description

Recombinant Protein

Recombinant Human R-Spondin-3 is a 26.9 kDa protein consisting of 240 amino acid residues. Due to glycosylation, R-Spondin-3 migrates at an apparent molecular weight of approximately 37.0 kDa by SDS PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9BXY4
For Use With (Application) Functional Assay
Formulation protein with no preservative
Gene ID (Entrez) 84870
Molecular Weight (g/mol) 26.9 kDa
Name Human R-Spondin-3
Quantity 20 μg
Source CHO cells
Regulatory Status RUO
Endotoxin Concentration <1 EU/ μg
Gene Alias 2810459H04Rik; AW742308; Cabriolet; cristin 1; Cristin1; cristin-1; cysteine-rich and single thrombospondin domain-containing protein 1; hPWTSR; hRspo3; Nucleopondin; protein with TSP type-1 repeat; PWTSR; RGD1563246; Roof plate-specific spondin-3; Rspo3; R-spondin 3; R-spondin 3 homolog; R-spondin 3 homolog (Xenopus laevis); R-spondin 3-like protein; R-spondin-3; Thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain 2; thrombospondin, type I, domain containing 2; Thsd2; Unknown (protein for MGC:137973)
Common Name RSPO3
Gene Symbol RSPO3
Biological Activity R-Spondin-3 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 for this effect is 0.8 -2.0 ug/ml
Conjugate Unconjugated
Recombinant Recombinant
Sequence MHPNVSQGCQ GGCATCSDYN GCLSCKPRLF FALERIGMKQ IGVCLSSCPS GYYGTRYPDI NKCTKCKADC DTCFNKNFCT KCKSGFYLHL GKCLDNCPEG LEANNHTMEC VSIVHCEVSE WNPWSPCTKK GKTCGFKRGT ETRVREIIQH PSAKGNLCPP TNETRKCTVQ RKKCQKGERG KKGRERKRKK PNKGESKEAI PDSKSLESSK EIPEQRENKQ QQKKRKVQDK QKSVSVSTVH
Content And Storage -20°C
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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