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  7. JNJ 5207852 dihydrochloride, Tocris Bioscience™

JNJ 5207852 dihydrochloride, Tocris Bioscience™

Product Code. 18036042
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Quantity:
10 mg
50 mg
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Description

High affinity H3 receptor antagonist

High affinity histamine H3 receptor neutral antagonist (pKi values are 8.9 and 9.2 in rat and human respectively). Brain penetrant and orally active. Has 3- and 100-fold higher affinity than thioperamide (Cat. No. 0644) for rat and human H3 receptors respectively. Suppresses slow-wave sleep; exhibits wake-promoting effects in rodent arousal models.

Chemical Identifiers

CAS 398473-34-2
Molecular Formula C20H32N2O
Molecular Weight (g/mol) 316.489
InChI Key PTKHFRNHJULJKT-UHFFFAOYSA-N
Synonym unii-4i9ovb1g7d, 4i9ovb1g7d, 1-4-3-piperidinopropoxy benzyl piperidine, 1-4-3-piperidin-1-yl propoxy benzyl piperidine, 1-3-4-piperidin-1-ylmethyl phenoxy propyl piperidine, 1-3-4-piperidin-1-yl methyl phenoxy propyl piperidine, piperidine, 1-3-4-1-piperidinylmethyl phenoxy propyl, jnj 5207852 dihydrochloride
PubChem CID 2766326
IUPAC Name 1-[3-[4-(piperidin-1-ylmethyl)phenoxy]propyl]piperidine
SMILES C1CCN(CC1)CCCOC2=CC=C(C=C2)CN3CCCCC3

Specifications

Quantity 50 mg
Formula Weight 389.4
Percent Purity >99%
Chemical Name or Material JNJ 5207852 dihydrochloride
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