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JZP 361, >99%, Tocris Bioscience™
Potent and selective reversible MAGL inhibitor
Brand: Tocris Bioscience 5851/50
2520.02 DKK valid until 2024-12-16
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Description
Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.Specifications
| [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- | |
| >99% | |
| 50 mg | |
| 405.88 |
| 1680193-80-9 | |
| C22H20ClN5O | |
| Soluble to 100mM in DMSO and to 20mM in ethanol |