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Ko 143, Tocris Bioscience™
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Quantity:
1 mg
10 mg
Description
Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Inhibits ABCB1 and ABCC1 at higher concentrations. Rapidly metabolized in rat plasma.
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Specifications
Specifications
Quantity | 1 mg |
Formula Weight | 469.57 |
Percent Purity | >99% |
Chemical Name or Material | Ko 143 |
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