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Megestrol Acetate, Tocris Bioscience™

Product Code. 30000889
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Quantity:
50 mg
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Description

Synthetic progesterone analog

Synthetic progesterone analog. Dose-dependently inhibits growth of HepG2 cells (IC50 = 260 μM) in vitro and in vivo and reduces tumor volume. High dosages improve weight gain in tumor-bearing nude mice. Orally bioavailable.

Specifications

CAS 595-33-5
Molecular Formula C24H32O4
Linear Formula C24H32O4
Quantity 50 mg
Synonym megestrol acetate, niagestin, megace es, megestryl acetate, megace, megeron, ovaban, ovarid, pallace, magestin
Solubility Information Soluble to 50mM in DMSO and to 20mM in ethanol
InChI Key RQZAXGRLVPAYTJ-GQFGMJRRSA-N
SMILES CC1=CC2C(CCC3(C2CCC3(C(=O)C)OC(=O)C)C)C4(C1=CC(=O)CC4)C
IUPAC Name [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Molecular Weight (g/mol) 384.516
PubChem CID 11683
Formula Weight 384.51
Percent Purity >98%
Physical Form Solid
Chemical Name or Material 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione
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