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Proteintech™ Mouse CXCL2 ELISA Kit

KE10022 is a solid phase sandwich Enzyme Linked-Immuno-Sorbent Assay (Sandwich ELISA). The CXCL2 ELISA kit is to be used to detect and quantify protein levels of endogenous CXCL2.

Brand:  Proteintech™ KE10022-96T


Product Code. 16831616

  • 2007.00 DKK / 96 tests

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Description

Description

  • The assay recognizes mouse CXCL2. An antibody specific for CXCL2 has been pre-coated onto the microwells.
  • The CXCL2 protein in samples is captured by the coated antibody after incubation. Following extensive washing, another antibody of biotinylated specific for CXCL2 is added to detect the captured CXCL2 protein.
  • For signal development, Streptavidin-HRP is added, followed by Tetramethyl-benzidine (TMB) reagent.
  • Solution containing sulfuric acid is used to stop color development and the color intensity which is proportional to the quantity of bound protein is measurable at 450nm with the correction wavelength set at 630 nm
  • Cxcl2, also known as macrophage inflammatory protein 2-alpha (Mip2-alpha), is a member of CXC chemokine family that binds to CXC chemokine receptor 2 (Cxcr2).
  • Cxcl2 is mainly produced by macrophages, endothelial cells, epithelial cells and tumor cells. Cxcl2 plays important roles in various biological progresses such as angiogenesis, inflammation, immune response and cancer biological behaviors.
  • Under inflammatory conditions in CNS, microglia and astrocytes may secrete Cxcl2 as well as other chemokines, which induces chemotaxis and infiltration of circulatory neutrophils.
  • Indeed, previous studies suggest that Cxcl2 is involved in Alzheimer disease, multiple sclerosis and brain ischemia.
Specifications

Specifications

NP_033166
20.5 pg/mL
Sandwich ELISA, Double Antibody
Plasma, Serum
Mouse
Mouse
<10%
Blue ice
4.5 hr.
31.25 to 500 pg/mL
ISO 13485
Coated ELISA Kit
DAB
20310
Solid
<10%
-20°C to +4°C
P10889
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Proteintech™ Mouse CXCL2 ELISA Kit > Target Species: Mouse

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