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N,O-Dimethylhydroxylamine hydrochloride, 98%, Thermo Scientific Chemicals
Description
N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
N,O-Dimethylhydroxylamine hydrochloride is used as a reagent in the preparation of 2-acyloxazoles from 2-oxazolemagnesium chloride and N-methoxy-N-methyl-3-oxo-butyramide from diketene. It is also used in amide coupling reactions to form Weinreb amides, which are useful in the Weinreb ketone synthesis. In addition, it is used in the preparation of an inhibitor of the NLS-derived BC peptides.
Solubility
Soluble in water, dimethyl sulfoxide and methanol.
Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
Specifications
Specifications
Melting Point | 112°C to 115°C |
Quantity | 100 g |
Beilstein | 3650353 |
Sensitivity | Hygroscopic |
Solubility Information | Soluble in water,dimethyl sulfoxide and methanol. |
IUPAC Name | N-methoxymethanamine;hydrochloride |
Formula Weight | 97.55 |
Percent Purity | 98% |
Chemical Name or Material | N,O-Dimethylhydroxylamine hydrochloride |
Safety and Handling
- N,O-Dimethylhydroxylamine hydrochloride
- Warning
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- MIXTURE LIST-Contains : N,O-Dimethylhydroxylamine hydrochloride
RUO – Research Use Only
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