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PF 04457845, Tocris Bioscience™

Potent and selective irreversible FAAH inhibitor

Brand: Tocris Bioscience 6374/25

Product Code. 15903271

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Description

PF 04457845 is a potent and selective irreversible FAAH inhibitor (IC50 = 7.2 nM, which is selective for FAAH over a panel of other serine hydrolases. PF 04457845 exhibits efficacy in a rat inflammatory pain model, and is orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material	N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide
CAS	1020315-31-4
Assay Percent Range	>98%
Quantity	25 mg

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PF 04457845, Tocris Bioscience™

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