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Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format
Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.
Brand: Thermo Scientific™ A39268
This item is not returnable.
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Description
Thermo Scientific™ Pierce Sulfo-SMCC is a very popular, water-soluble, amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane spacer arm (8.3 Ås).
- Reactive groups: sulfo-NHS ester and maleimide
- Reactive towards: amino and sulfhydryl groups
- Water-soluble (compare to SMCC), so crosslinking can be done in physiologic solutions
- High purity, crystalline reagent can be used to create high-purity maleimide-activated derivatives
- Cyclohexane bridge confers added stability to the maleimide group making Sulfo-SMCC the ideal crosslinking agent for maleimide activation of proteins. Maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7 at 4°C.
Specifications
| Amine-Sulfhydryl | |
| Sulfo-SMCC | |
| No | |
| Upon receipt store desiccated at -20°C. | |
| Ambient | |
| Chemical Labeling | |
| Maleimide, Sulfo-NHS Ester | |
| Solid | |
| Water | |
| Yes |
| No | |
| 436.37 | |
| 8.3 Å | |
| No | |
| No-Weigh™ | |
| Heterobifunctional | |
| Short (<10 Å) | |
| 10 x 2 mg | |
| Standard, Single-use, Premium-grade | |
| Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.