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Rottlerin, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Originally reported to inhibit PKC isoforms. Also reported to inhibit CAM kinase III. However, recently shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Also shown to act as a direct mitochondrial uncoupler. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways.
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Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 516.55 |
Percent Purity | >98% |
Chemical Name or Material | Rottlerin |
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