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  6. (S)-(+)-Dimethindene maleate, Tocris Bioscience™

(S)-(+)-Dimethindene maleate, Tocris Bioscience™

Product Code. 18782604
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Quantity:
10 mg
50 mg
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Beschreibung

M2-selective antagonist

(S)-(+)-Dimethindene maleate is an enantiomer that is a subtype-selective M2 muscarinic receptor antagonist (pKi values are 7.08, 7.78, 6.70 and 7.00 for M1, M2, M3 and M4 receptors respectively). Also H1 histamine receptor antagonist (pKi = 7.48). Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), minocycline hydrochloride (Cat.No. 3268) and human leukemia inhibitory factor.

For more information about how Dimethindene maleate may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .

Chemische Identifikatoren

CAS 136152-65-3
Molecular Formula C24H28N2O4
Molecular Weight (g/mol) 408.498
InChI Key SWECWXGUJQLXJF-HFNHQGOYSA-N
Synonym s-+-dimethindene maleate, unii-j43zl3wtln, dimethindene maleate, +, j43zl3wtln, dsstox_cid_28966, dsstox_rid_83231, dsstox_gsid_49040, dimethindene maleate, s-+, d0zj1c, 1h-indene-2-ethanamine, n,n-dimethyl-3-1s-1-2-pyridinyl ethyl-, 2z-2-butenedioate 1:1
PubChem CID 56972160
IUPAC Name (Z)-but-2-enedioic acid;N,N-dimethyl-2-[3-[(1S)-1-pyridin-2-ylethyl]-1H-inden-2-yl]ethanamine
SMILES CC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C.C(=CC(=O)O)C(=O)O

Spezifikation

Quantity 10 mg
Formula Weight 408.5
Percent Purity >99%
Chemical Name or Material (S)-(+)-Dimethindene maleate
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