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Tamibarotene, Thermo Scientific Chemicals Product Code.: 15456159
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Tamibarotene, Thermo Scientific Chemicals

Product Code. 15456159
50 mg
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Quantity:
10 mg
50 mg
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Product Code. 15456159

Brand: Thermo Scientific Alfa Aesar J64028.MF

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Description

A retinoic acid receptor → (RAR→) agonist

Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 ?M respectively).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively).

Solubility
Soluble to 50 mM in DMSO

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 94497-51-5
Molecular Formula C22H25NO3
Molecular Weight (g/mol) 351.45
MDL Number MFCD00866188
InChI Key MUTNCGKQJGXKEM-UHFFFAOYSA-N
Synonym tamibarotene, retinobenzoic acid, 4-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl carbamoyl benzoic acid, amnolake, tamibaro, amnoid, unii-08v52gz3h9, 4-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl carbamoyl benzoic acid, chembl25202
PubChem CID 108143
ChEBI CHEBI:32181
IUPAC Name 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
SMILES CC1(C)CCC(C)(C)C2=CC(NC(=O)C3=CC=C(C=C3)C(O)=O)=CC=C12

Specifications

Color White
Quantity 50 mg
Merck Index 14,9047
Solubility Information Soluble to 50 mM in DMSO
Formula Weight 351.44
Physical Form Solid
Chemical Name or Material Tamibarotene

Certificates

Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZ03K007 Certificate TypeCertificate of Analysis Date04/12/2024 Catalog NumberJ64028.MF,J64028.MA
Lot NumberX04J038 Certificate TypeCertificate of Analysis Date25/10/2023 Catalog NumberJ64028.MF,J64028.MA
Lot NumberZ22A006 Certificate TypeCertificate of Analysis Date08/12/2021 Catalog NumberJ64028.MF,J64028.MA
Lot NumberS30G030 Certificate TypeCertificate of Analysis Date06/12/2021 Catalog NumberJ64028.MF,J64028.MA
Lot NumberR09A015 Certificate TypeCertificate of Analysis Date06/12/2021 Catalog NumberJ64028.MF,J64028.MA

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