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Thermo Scientific™ Tango™ DRD1-bla U2OS Cells
The Tango™ DRD1-bla U2OS cells contain the human Dopamine Receptor 1 (DRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Brand: Thermo Scientific™ K1485
This item is not returnable.
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Description
The Tango™ DRD1-bla U2OS cells contain the human Dopamine Receptor 1 (DRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.
The Tango™ DRD1-bla U2OS cell line has been functionally validated for Z'-factor and EC50 concentrations of dihydrexidine. The DRD1 cells have been tested for assay performance under variable assay conditions. These data are available in the Validation & Assay Performance Summary in the Manuals and Brochures section.
Specifications
| NM_000794.2 | |
| Dividing Cells | |
| Tail from AVPR2 GPCR | |
| GPCRs | |
| DRD1-bla U2OS cells, DRD1-bla U2OS Assay Protocol, Certificate of Analysis | |
| Tango™ | |
| BLA (Beta-Lactamase) | |
| U2OS Cell | |
| Tango™ |
| Cell-based beta-arrestin recruitment | |
| LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • Tango™ DRD1-bla U2OS cells • Tango™ DRD1-bla U2OS Assay Protocol • Certificate of Analysis The Tango™ DRD1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
|
| Fluorescence | |
| DRD1 | |
| Single Cell Clone Origin | |
| 2 x 106 Cells | |
| DRD1, D1 | |
| U2OS | |
| GPCR |
For Research Use Only. Not for use in diagnostic procedures.