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TMEM110 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA570169
This item is not returnable.
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Description
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574). SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679). Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679). Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574). Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574). [UniProt]
Specifications
| TMEM110 | |
| Polyclonal | |
| Unconjugated | |
| TMEM110 | |
| 1810038N08Rik; 2310014H19Rik; AW554125; STIM-activating enhancer; STIM-activating enhancer encoded by TMEM110; STIMATE; Store-operated calcium entry regulator STIMATE; Tmem110; Transmembrane protein 110 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 361110 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q7TSW6 | |
| TMEM110 | |
| synthetic peptide corresponding to a region of rat TMEM110 | |
| 100 μL | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |