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Tocris Bioscience™ UNC 0642

Potent and selective G9a and GLP inhibitor

Brand:  Tocris Bioscience™ 5132/50

8363.50 DKK valid until 2024-12-16
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Product Code. 18761819

  • 10570.00 DKK / 50mg

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Description

Description

UNC 0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM) that exhibits >2,000-fold selectivity for G9a and GLP over PRC2-EZH2 and >20,000-fold selectivity over other methyltransferases. UNC 0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM), and displays modest brain penetration in vivo.
Specifications

Specifications

>99%
50 mg
546.7
-20°C
UNC 0642
UNC 0642
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