Isotope Standards
Isotope Standards
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Losartan (D4 Carboxylic Acid), MedChemExpress
MedChemExpress Losartan D4 Carboxylic Acid (E-3174 D4) is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist.
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Molecular Weight (g/mol) | 440.92 |
---|---|
Color | Off-White |
Physical Form | Powder |
Chemical Name or Material | Losartan (D4 Carboxylic Acid) |
Grade | Research |
SMILES | ClC1=C(C(O)=O)N(CC2=C([2H])C([2H])=C(C3=CC=CC=C3C4=NN=NN4)C([2H])=C2[2H])C(CCCC)=N1 |
For Use With (Application) | Metabolism-protein/nucleotide metabolism |
CAS | 1246820-62-1 |
Synonym | E-3174 D4 EXP-3174 D4 |
Purity Grade Notes | Research |
Recommended Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Shelf Life | Please store the product under the recommended conditions in the Certificate of Analysis. |
Molecular Formula | C22H17D4ClN6O2 |
Formula Weight | 440.92 |
Omeprazole-d3, MedChemExpress
MedChemExpress Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.
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VX-984, MedChemExpress
MedChemExpress VX-984 (M9831) is an orally active, potent, selective and BBB-penetrated DNA-PK inhibitor. VX-984 efficiently inhibits NHEJ (non-homologous end joining) and increases DSBs (DNA double-strand breaks). VX-984 can be used for glioblastomas (GBM) and non-small cell lung cancer (NSCLC) research.
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Molecular Weight (g/mol) | 415.49 |
---|---|
Color | White |
Physical Form | Solid |
Chemical Name or Material | VX-984 |
Grade | Research |
SMILES | O=C(C1=CC=NC2=C([C@H](C)CNC3=CC(C4=C([2H])N=C(C)N=C4[2H])=NC=N3)C=CC=C12)NC |
For Use With (Application) | Cancer-Kinase/protease |
Percent Purity | 98.34% |
CAS | 1476074-39-1 |
Solubility Information | DMSO : 10 mg/mL (24.07 mM; Need ultrasonic) |
Synonym | M9831 |
Purity Grade Notes | Research |
Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Molecular Formula | C23H21D2N7O |
Formula Weight | 415.49 |
Proguanil-d6, MedChemExpress
MedChemExpress Proguanil D6 is the deuterium labeled Proguanil, which is a prophylactic antimalarial drug.
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Candesartan-d4, MedChemExpress
MedChemExpress Candesartan D4 (CV-11974 D4) is the deuterium labeled Candesartan, which is an angiotensin II receptor antagonist.
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Molecular Weight (g/mol) | 444.48 |
---|---|
Color | White |
Physical Form | Solid |
Chemical Name or Material | Candesartan-d4 |
Grade | Research |
SMILES | [2H]C1=C(CN2C(C(C(O)=O)=CC=C3)=C3N=C2OCC)C([2H])=C([2H])C(C4=CC=CC=C4C5=NNN=N5)=C1[2H] |
Percent Purity | 98.85% |
CAS | 1346604-70-3 |
Synonym | CV-11974-d4 |
Purity Grade Notes | Research |
Recommended Storage | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
Shelf Life | 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture) |
Molecular Formula | C24H16D4N6O3 |
Formula Weight | 444.48 |
MMAE-d8, MedChemExpress
MedChemExpress MMAE-d8 (Monomethyl auristatin E-d8) is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.
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Molecular Weight (g/mol) | 726.03 |
---|---|
Color | White |
Physical Form | Solid |
Chemical Name or Material | MMAE-d8 |
Grade | Research |
SMILES | CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@@](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])([2H])NC([C@H](C(C)C)NC)=O)=O)C |
For Use With (Application) | Cancer-programmed cell death |
Percent Purity | 98.43% |
CAS | 2070009-72-0 |
Solubility Information | DMSO : 100 mg/mL (137.74 mM; Need ultrasonic) |
Synonym | Monomethyl auristatin E-d8 Deuterated labeled MMAE |
Purity Grade Notes | Research |
Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended. |
Shelf Life | Powder -20°C 3 years, 4°C 2 years∣The compound is unstable in solutions, freshly prepared is recommended. |
Molecular Formula | C39H59D8N5O7 |
Formula Weight | 726.03 |
Nitazoxanide-d4, MedChemExpress
MedChemExpress Nitazoxanide D4 (NTZ D4) is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.
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Molecular Weight (g/mol) | 311.31 |
---|---|
Color | Off-White |
Physical Form | Solid |
Chemical Name or Material | Nitazoxanide-d4 |
Grade | Research |
SMILES | O=C(NC1=NC=C([N+]([O-])=O)S1)C2=C(OC(C)=O)C([2H])=C([2H])C([2H])=C2[2H] |
Percent Purity | 98.0% |
CAS | 1246819-17-9 |
Synonym | NTZ-d4 NSC-697855-d4 |
Purity Grade Notes | Research |
Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Molecular Formula | C12H5D4N3O5S |
Formula Weight | 311.31 |
Enalaprilat D5, MedChemExpress
MedChemExpress Enalaprilat D5 (MK-422 D5) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.
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Tetrabenazine-d6, MedChemExpress
MedChemExpress Tetrabenazine D6 is the deuterium labeled Tetrabenazine, which is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder.
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Molecular Weight (g/mol) | 323.46 |
---|---|
Color | Off-White |
Physical Form | Solid |
Chemical Name or Material | Tetrabenazine-d6 |
Grade | Research |
SMILES | O=C1[C@H](CC(C)C)CN2CCC3=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C3[C@@]2([H])C1 |
For Use With (Application) | Neuroscience-Neuromodulation |
Percent Purity | 98.3% |
CAS | 1392826-25-3 |
Synonym | Ro 1-9569-d6 |
Purity Grade Notes | Research |
Recommended Storage | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
Shelf Life | 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
Molecular Formula | C19H21D6NO3 |
Formula Weight | 323.46 |
Enalaprilat-d5 sodium, MedChemExpress
MedChemExpress Enalaprilat (MK-422) D5 Sodium Salt is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.
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Mycophenolic acid-d3, MedChemExpress
MedChemExpress Mycophenolic acid D3 (Mycophenolate D3) is deuterium labeled Mycophenolic acid, which is an an immunosuppresant drug and has potent anti-proliferative activity.
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Molecular Weight (g/mol) | 323.36 |
---|---|
Color | White |
Physical Form | Solid |
Chemical Name or Material | Mycophenolic acid-d3 |
Grade | Research |
SMILES | O=C(OC1)C2=C1C(C)=C(OC([2H])([2H])[2H])C(C/C=C(C)/CCC(O)=O)=C2O |
Percent Purity | 98.0% |
CAS | 1185242-90-3 |
Synonym | Mycophenolate-d3 |
Purity Grade Notes | Research |
Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
Molecular Formula | C17H17D3O6 |
Formula Weight | 323.36 |
Vilazodone-d8, MedChemExpress
MedChemExpress Vilazodone D8 is the a deuterium labeled vilazodone, which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist.
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