General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ Tango™ HRH3-bla U2OS DA Assay Kit
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Tango™ AGTRL1-bla U2OS Cells
The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Kinase Tracer 236, 50 μM
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Invitrogen™ BacMam LRRK2-GFP G2019S Reagent
BacMam LRRK2-GFP G2019S Reagent is a modified insect cell virus (baculovirus) that enables easy, efficient, and titratable overexpression of full-length LRRK2-GFP G2019S in your choice of cellular background, including primary neurons and neuroblastoma cell lines.
Thermo Scientific™ GeneBLAzer™ MC5R-CRE-bla CHO-K1 Cells
GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 5 (MC5R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
GeneBLAzer™ GeneBLAzer™ GIPR-CRE-bla HEK 293T Cells
GeneBLAzer™ GIPR-CRE-bla HEK 293T Cells contain the human Gastric Inhibitory Peptide Receptor (GIPR).
Thermo Scientific™ GeneBLAzer™ MC2R CHO-K1 DA Assay Kit
The GeneBLAzer™ MC2R CHO-K1 DA (Division Arrested) cells contain the human melanocortin-2 receptor (MC2R), and the Melanocortin-2 receptor accessory protein (MRAP), stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ GALR2-bla U2OS Cells
The Tango™ GALR2-bla U2OS cells contain the human Galanin Receptor 2 (GALR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ CXCR1-bla U2OS Cells
The Tango™ CXCR1-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 1 (CXCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ irf1-bla TF-1 Cell Line
Jak/Stat signaling pathways play essential roles in cellular responses to distinct cytokines. One of the Jak/Stat pathways, Jak2/Stat5, mediates cell proliferation in response to Interleukin-3 (IL-3), prolactin, erythropoietin (Epo), and granulocyte-macrophage colony stimulating factor (GM-CSF).
Thermo Scientific™ LanthaScreen™ PRAS40 293E Cell Line
The PI3K/AKT pathway is activated by various stimuli (including insulin and IGF-1) and mediates signals for cell growth, cell survival, translation, and inhibition of apoptosis.
Thermo Scientific™ GeneBLAzer™ PTGDR CHO-K1 DA Assay Kit
GeneBLAzer™ PTGDR CHO-K1 DA (Division Arrested) cells and PTGDR-CRE-bla CHO-K1 cells contain the human Prostanoid (PTGDR) receptor stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ SBE-bla A375 Cell Line
Bone morphogenetic proteins (BMPs), members of the transforming growth factor beta (TGF-β) superfamily, play important roles in the development of the heart, central nervous system and cartilage.