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Glibenclamide, MedChemExpress
MedChemExpress Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity.
Brand: Medchem Express HY-15206
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Description
Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.Specifications
| Glibenclamide | |
| White | |
| C23H28ClN3O5S | |
| Glyburide | |
| ClC1=CC(C(NCCC2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)=O)=C(OC)C=C1 | |
| 494.0 | |
| Research | |
| Metabolism-protein/nucleotide metabolism |
| 10238-21-8 | |
| Research | |
| 1 g | |
| DMSO : 250 mg/mL (506.07 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.20 mM; Need ultrasonic and warming) | |
| 494.0 | |
| 98.89% | |
| Solid |
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Product Title
Glibenclamide, MedChemExpress
Research purposes only
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