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Glibenclamide, MedChemExpress

MedChemExpress Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity.

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684.84 DKK - 956.77 DKK

Specifications

Chemical Name or Material Glibenclamide
CAS 10238-21-8
Color White
Purity Grade Notes Research
Molecular Formula C23H28ClN3O5S
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Description

Description

Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.
Specifications

Specifications

Glibenclamide
White
C23H28ClN3O5S
DMSO : 250 mg/mL (506.07 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.20 mM; Need ultrasonic and warming)
494.0
98.89%
Solid
10238-21-8
Research
Glyburide
ClC1=CC(C(NCCC2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)=O)=C(OC)C=C1
494.0
Research
Metabolism-protein/nucleotide metabolism
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Safety and Handling

Safety and Handling

H302∣H413

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

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Product Certifications

Research purposes only

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