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Tocris Bioscience™ H 151

STING antagonist

Brand:  Tocris Bioscience™ 6675/10

1418.54 DKK valid until 2024-12-16
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Product Code. 18717606

  • 1855.00 DKK / 10mg

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Description

Description

H 151 is a STING antagonist. Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters. Decreases inflammatory cytokine production in human and mouse cells in vitro. Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease.
Specifications

Specifications

N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea
ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173
STING Antagonists
279.34
941987-60-6
10 mg
C17H17N3O
98%
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