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Specifications
| Chemical Name or Material | N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea |
|---|---|
| CAS | 941987-60-6 |
| Synonym | ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173 |
| Target | STING Antagonists |
| Molecular Formula | C17H17N3O |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18717606
|
Tocris Bioscience™
6675/10 |
10 mg |
1855.00 DKK
10mg |
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|
18769306
|
Tocris Bioscience™
6675/50 |
50 mg |
6680.00 DKK
50mg |
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Description
- Covalently binds STING at Cys91, blocking palmitoylation and preventing assembly of STING clusters
- Decreases inflammatory cytokine production in human and mouse cells in vitro
- Also blocks CMA (Cat. No. 6677) -induced increases in levels of inflammatory cytokines in mice, and alleviates systemic inflammation in a mouse model of autoinflammatory disease
Specifications
| N-(4-Ethylphenyl)-N'-1H-indol-3-yl-urea | |
| ERIS, hMITA, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, sting, transmembrane protein 173 | |
| C17H17N3O | |
| 98% |
| 941987-60-6 | |
| STING Antagonists | |
| 279.34 |
Safety and Handling
Recommended Storage : Store at 4°C