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Thermo Scientific™ LC-SPDP (succinimidyl 6-(3(2-pyridyldithio)propionamido)hexanoate)

Crosslink amines to sulfhydryls with this crosslinker composed of NHS-ester and pyridyldithiol groups at ends of 10-atom (15.7A) spacer arm.

Brand:  Thermo Scientific™ 21651

Product Code. 11811255

  • 4665.00 DKK / 50mg

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Description

Description

Thermo Scientific™ Pierce LC-SPDP is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

Highlights:

  • Forms cleavable disulfide bonds with sulfhydryls
  • Releases a detectable byproduct after reacting with a free sulfhydryl group; by measuring the release of pyridine-2-thione at 343nm, the reaction can be monitored
  • Reactive groups: NHS ester and pyridyldisulfide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Sulfhydryl
LC-SPDP
No
Upon receipt store at 4°C protected from moisture.
Ambient
Chemical Labeling
NHS Ester, Pyridyldisulfide
Powder
DMF, DMSO
No
By Thiols
425.52
15.7 Å
Yes
Pierce™
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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Product Information

Manuals

User Guide: SPDP Crosslinkers Version: Jan. 2015 File size: 110.2 kB
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Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZI393049 Certificate TypeCertificate of Analysis Date15/10/2024 Catalog Number21651
Lot NumberZB386500 Certificate TypeCertificate of Analysis Date08/03/2024 Catalog Number21651
Lot NumberYI377302 Certificate TypeCertificate of Analysis Date18/10/2023 Catalog Number21651
Lot NumberSPECS Certificate TypeCertificate of Analysis Date18/10/2023 Catalog Number21651
Lot NumberYC344091 Certificate TypeCertificate of Analysis Date08/04/2023 Catalog Number21651
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Product Title
Thermo Scientific™ LC-SPDP (succinimidyl 6-(3(2-pyridyldithio)propionamido)hexanoate) > 50mg

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For Research Use Only. Not for use in diagnostic procedures.