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TDP-43 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1081.84 DKK - 3058.99 DKK

Specifications

Antigen TDP-43
Concentration 0.31 mg/mL
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunohistochemistry, Flow Cytometry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16857393
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Proteintech
10782-2-AP-20UL
20 μL
1081.84 DKK
20µL
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16847393
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Proteintech
10782-2-AP-150UL
150 μL
3058.99 DKK
150µL
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Description

Description

Proteintech's 10782-2-AP antibody is a rabbit polyclonal antibody recognizing N-terminal TDP-43. It recognizes the intact 45 kDa protein as well as all post translationally modified and truncated forms in multiple applications. Various forms of TDP-

TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
Specifications

Specifications

TDP-43
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Immunohistochemistry, Flow Cytometry
Unconjugated
Rabbit
Rat, Zebrafish, Mouse, Human
Q13148, Q921F2
230908, 23435, 298648, 325052
TDP-43 Fusion Protein Ag1231
Primary
-20°C
TARDBP
0.31 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ALS10, TAR DNA binding protein, TAR DNA binding protein 43, TARDBP, TDP 43, TDP43
tardbp
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications