missing translation for 'onlineSavingsMsg'
Learn More

TDP-43 Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10782-2-AP-150UL

 View more versions of this product

Product Code. 16847393

  • 3058.99 DKK / 150µL

Please to purchase this item. Need a web account? Register with us today!

Explore more special offers
This item is not returnable. View return policy

Description

Description

Proteintech's 10782-2-AP antibody is a rabbit polyclonal antibody recognizing N-terminal TDP-43. It recognizes the intact 45 kDa protein as well as all post translationally modified and truncated forms in multiple applications. Various forms of TDP-

TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
Specifications

Specifications

TDP-43
Polyclonal
Unconjugated
TARDBP
ALS10, TAR DNA binding protein, TAR DNA binding protein 43, TARDBP, TDP 43, TDP43
Rabbit
Antigen Affinity Chromatography
RUO
230908, 23435, 298648, 325052
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q13148, Q921F2
tardbp
TDP-43 Fusion Protein Ag1231
150 μL
Primary
Human, Mouse, Rat, Zebrafish
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers