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Entacapone, MedChemExpress

MedChemExpress Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor.

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624.42 DKK - 1873.25 DKK

Specifications

Chemical Name or Material Entacapone
CAS 130929-57-6
Color Yellow
Purity Grade Notes Research
Molecular Formula C14H15N3O5
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100 mg
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Description

Description

Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 μM). Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.
Specifications

Specifications

Entacapone
Yellow
C14H15N3O5
O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1
305.29
Research
Neuroscience-Neurodegeneration
130929-57-6
Research
DMSO : 33.33 mg/mL (109.17 mM; Need ultrasonic) ∣H2O : 2 mg/mL (6.55 mM; ultrasonic and adjust pH to 10 with NaOH)
305.29
98.79%
Powder
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

Documents

Product Certifications

Research purposes only

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